From the very start, what you need to worry about first and foremost is understanding the track as a whole. As most kart circuits are relatively short, if you mess up a single corner it's very hard to regain the time lost throughout the rest of the lap (either side of the main straight).
Example, if you nail the slowest corner on the track, the next few faster corners you will carry that much more momentum and be ultimately faster. As they are underpowered, it's hard to regain that lost speed within a lap. Consistency is paramount - there is no point in setting a blistering lap time, if the next lap you lose 20% of your lap time due to getting the entry to a single corner wrong.
Also, bananas and red shells are key to winning a race.